Some handy science-related analogies:
  • Axon guidance: how do you find your way?
  • Self/non-self: How can you tell if someone does or doesn't belong in a group?
  • Catalysis: match-making
  • DNA->RNA transcription: Why do you make copies of an important document instead of sending in the original? [ <- Katelen: did I remember this one correctly? ]
  • Chemiosmosis: letting people out of a crowded dance floor via a revolving door (which acts as a turbine)
  • Genes: like a recipe for a protein
  • Chromosomes: like a library
  • Recessives: like two lights in a hallway (on = dominant, off = recessive)
  • Rocks in a glass -> multigenic threshold traits (overfull -> mutant phenotype)

Some reasons why evolution matters:
  • Agriculture:
    • The source of improvements in agriculture, especially from QTL mapping
    • (for that matter, it's the source of agriculture, period)
    • Implications of GMOs, monoculture
    • Evolution of pesticide resistance

    Disease and medical ties:
    • development of vaccines and drugs
    • Affects disease organisms and their interaction with immune systems, changing how we should deal with them (bacterial resistance / public health)
    • helps predict spread of disease (epidemiology)
    • Cancer as a byproduct of somatic evolution
    • The vertebrate immune system is itself an ongoing example of somatic evolution (clonal selection)
    • Some indication that the brain develops via selection of generated connections
    • Inherited conditions
    • Inherited "normal" traits

  • Manufacturing
    • Human directed evolution: chemical synthesis; production of energy (biofuels)

  • Tools for biologists:
    • "selection" experiments (versus "screen" experiments): Can save time by a factor of 1000x or more
    • Form follows function => we can infer function from form. (examples: DNA structure; protein motif identification) This is the basis of bioinformatics
    • For phylogenetics: lets you find nearest relatives; nearest relatives tend to share traits. Understanding which traits have a common origin affects inference of environmental forces, choice of model organisms.

  • Identifying organisms and their relationships:
    • helps understanding of forces in nature / ecology
    • lets us know just what organisms exist
    • helps identify population structure within a species (this includes humans)
    • helps figure out population history (this includes humans, too)
    • This lets us learn about historical constraints.

  • Ecology ties
    • importance of diversity
    • help support endangered species; how big a population is enough to be stable?
    • Life history theory (trade-offs to deal with constraints)
    • Game theory (interaction between different organismal strategies)
    • Helps resource management (fisheries)
    • Coevolution (host/parasite; symbiotic)
    • Human (accidental) impact on evolution of other organisms

  • Ideas/memes
    • Improvement through trial and error (genetic algorithms / importance sampling)
    • Inspiration for innovation (competition as productive; use of natural world as source of ideas)
    • Has inspired new methods of critical analysis (evolutionary perspectives on perception of art, music, literature, etc.)
    • understanding sexual selection has changed views of "natural" gender roles
    • Linguistic evolution: history of words, language use, manuscript versions
    • Social: "memes"
    • the evolution of ideas, jokes
    • More social stuff: evolution of society, economies, nations, ethical systems, religions, etc.
    • Evolutionary game theory applies to patterns of human behavior as well as to (other) natural populations

  • Serendipity
    • Most of the big jumps caused by science and technology have been a surprise.



This page has been intentionally left free of narwhals.